MARBURG VIRUS VP35 CAN BOTH FULLY COAT THE BACKBONE AND CAP THE ENDS OF DSRNA FOR INTERFERON ANTAGONISM.

Filoviruses, including Marburg virus (MARV) and Ebola virus (EBOV), cause fatal hemorrhagic fever in humans and non-human primates.All filoviruses encode a unique multi-functional protein termed VP35.The C-terminal double-stranded (ds)RNA-binding domain (RBD) of VP35 has been implicated in interferon antagonism and immune evasion.Crystal structures

The paper explores the relationship between the Draft Global Pact for the Environment (the Global Pact) and relevant international documents (declarations and international environmental agreements) and the legislation of Republic of Serbia (RS).The first part of the article provides a survey of the contents of the Global Pact, pointing to the sign